Antioxidants are a group of compounds that play a vital role in the body's defence mechanism against the damage caused by free radicals. Free radicals are unstable molecules that can damage cells, proteins, and DNA, leading to premature ageing, chronic diseases, and even cancer. Antioxidants work by neutralising free radicals, thereby preventing oxidative stress and promoting healthy cell function.
Antioxidants in skincare products are vital due to their ability to combat signs of ageing and promote healthy skin. Tocopherols, a group of antioxidants that include vitamin E, are particularly important in skincare due to their ability to protect against UV damage, improve skin hydration, and reduce inflammation.
Function and Mechanism of Antioxidants in Skincare:
When applied topically, antioxidants work by neutralising free radicals in the skin. This is particularly important in the case of UV damage, which can cause significant oxidative stress and damage to skin cells. By neutralising free radicals, antioxidants help to prevent the breakdown of collagen and elastin, two essential components of healthy skin that contribute to its elasticity and firmness.
Tocopherols, in particular, have been shown to be effective in protecting the skin against UV damage. Studies have demonstrated that topical application of tocopherols can reduce UV-induced erythema (redness) and prevent the formation of sunburn cells, which are a marker of UV damage to the skin.
In addition to their UV-protective properties, tocopherols also have anti-inflammatory effects on the skin. Inflammation is a common cause of skin ageing, and tocopherols can help to reduce inflammation by inhibiting the production of pro-inflammatory cytokines and chemokines.
Benefits of Antioxidants in Skincare:
The benefits of antioxidants in skincare are numerous, and include:
- Protection Against UV Damage: As discussed above, antioxidants such as tocopherols can protect the skin against UV damage, which can cause premature ageing, sunburn, and even skin cancer.
- Improved Skin Hydration: Antioxidants can improve skin hydration by increasing the skin's natural moisture barrier. This can help to prevent dryness, flakiness, and other signs of dehydration.
- Reduced Inflammation: Inflammation is a common cause of skin ageing, and antioxidants can help to reduce inflammation by neutralising free radicals and inhibiting the production of pro-inflammatory cytokines.
- Increased Collagen Production: Antioxidants can stimulate the production of collagen, which is essential for healthy skin. Collagen contributes to skin elasticity and firmness, and its breakdown is a major contributor to the signs of ageing.
- Improved Skin Texture: Antioxidants can improve skin texture by promoting healthy cell function and reducing the appearance of fine lines, wrinkles, and other signs of ageing.
- Podda, M., Traber, M. G., & Weber, C. (1998). UV-irradiation depletes antioxidants and causes oxidative damage in a model of human skin. Free radical biology & medicine, 24(1), 55-65.
- Fuchs, J. (1998). Potential and limitation of the natural antioxidants RRR-alpha-tocopherol and L-ascorbic acid in cutaneous photoprotection. Free radical biology & medicine, 25(7), 848-873.
- Lin, F. H., Lin, J. Y., Gupta, R. D., Tournas, J. A., Burch, J. A., Selim, M. A., ... & Voorhees, J. J. (2003). Ferulic acid stabilizes a solution of vitamins C and E and doubles its photoprotection of skin. Journal of Investigative Dermatology, 123(2), 221-226.
- Burke, K. E. (2007). Mechanisms of aging and development--a new understanding of environmental damage to the skin and prevention with topical antioxidants. Mechanisms of ageing and development, 128(7-8), 443-449.
- Tominaga, K., Hongo, N., Fujishita, M., Takahashi, Y., Adachi, Y., & Nakagawa, H. (2010). Protective effects of astaxanthin on skin deterioration. Journal of clinical biochemistry and nutrition, 47(2), 105-115.
- Podda, M., Tritschler, H. J., Ulrich, H., Packer, L., & Takeda, K. (1996). Enzymatic and non-enzymatic antioxidants in epidermis and dermis of human skin. Journal of investigative dermatology, 106(6), 1228-1233.
- Lin, J. Y., & Selim, M. A. (2010). Shea butter: a cosmetic ingredient for mild UV protection and skin repair. Journal of functional foods, 2(1), 45-51.
- Korać, R. R., & Khambholja, K. M. (2011). Potential of herbs in skin protection from ultraviolet radiation. Pharmacognosy reviews, 5(10), 164.
- Thiele, J. J., Hsieh, S. N., & Ekanayake-Mudiyanselage, S. (2001). Vitamin E: critical review of its current use in cosmetic and clinical dermatology. Dermatologic surgery, 27(9), 805-816.